Squamous Cell Carcinoma : Description, Cause, Management And Advice For
Patient
Description
● A locally invasive malignant tumour of the epidermal keratinocytes or its
appendages, which has the potential to metastasise
Causes
● Risk factors include excessive UV exposure, pre-malignant skin conditions
(e.g. actinic keratoses), chronic inflammation (e.g. leg ulcers, wound
scars), immunosuppression and genetic predisposition
Presentation
● Keratotic (e.g. scaly, crusty), ill-defined nodule which may ulcerate
Management
● Surgical excision - treatment of choice
● Mohs micrographic surgery – may be necessary for ill-defined, large,
recurrent tumours
● Radiotherapy - for large, non-resectable tumours
Prognosis
● Depends on tumour size, site, histological pattern, depth of invasion,
perineural involvement, and immunosuppression
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Squamous Cell Carcinoma : Description, Cause, Management And Advice For Patient
Friday, December 28, 2018
Squamous Cell Carcinoma : Description, Cause, Management And Advice For Patient
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